I have learned at least one thing. From your posts I have learned that you oppose all government interference
Not true. There a places where government is good. For example, providing a (reasonable) military the repel invasion.
whether they be for the good of the people or not.
It would be good for the people to be required to exercise a prescribed amount every day. Do you think that should be made law? Who gets to decide what 'for the good of the people' The people in Washington? The most contemptible people on earth?
If they were to legalize drugs and give people the freedom to use, you claim this will help clean up the supply. That people will not be dieing because the supply of drugs they are consuming is dirty now. How do you know that is what will happen?
Economics 101.
Will government then regulate the supply in order to make sure it is safe for the people?
The government has food safety and drug safety standards. I don't disagree with the government making sure products sold across state lines, are reasonably regulated, to ensure safety, as that WOULD be completely constitutional.