... affected me most particularly at night and wrecked whatever sleep patterns that I had. A work colleague had noticed me taking a tablet with my lunch, and had asked me what I was taking. When I told her that I was taking statins, she asked if I experienced muscle problems. That was the first time that I connected the agonising cramps statins. I decided to lay off the statins for a few days just to see if they were the cause of the leg cramps at night. The cramps ceased almost immediately. I mentioned this to the GP, who prescribed me a different type of statin. The cramps re-appeared within a matter of days. Then a third variety was trialled; same result. Haven't been on statins since.