Heres a study that addresses the brain correlates of Neuroticism trait. ALthough NPA theory does not use the term as a key trait, neuroticism seems important as it permeates all traits that include negativity and misery and other bad things. NPA theory seems to asssociate it with P trait. What would be the purpose of feelings of misery? probably there is a survival value as, after all, we humans live in a hostile universe.
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