https://www.researchgate.net/profile/Rowan_Saloner/publication/342636368_COMT_Val158Met_Genotype_Alters_the_Effects_of_Methamphetamine_Dependence_on_Dopamine_and_Dopamine-related_Executive_Function_Preliminary_Findings/links/5f23984e299bf1340494c8dd/COMT-Val158Met-Genotype-Alters-the-Effects-of-Methamphetamine-Dependence-on-Dopamine-and-Dopamine-related-Executive-Function-Preliminary-Findings.pdf
Here is an example of how the usually high dopamine and thus more contemplative brain of those with this A- trait candidate gene are exquisitely sensitive to the effects of stimulants.
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