NPA personality theory
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Re: aggression trait gene and entanglement
Perhaps MAO is a major modifying locus of trait A. But in order for there to be entanglement* between traits N and A in the study, there would need to be a mechanism causing unequal partitioning of non-sanguine NPA types between the high and low aggression groups.
*Entanglement between traits N and A can occur in a case-control study because the lack of one of the two traits in an individual, or in a group, implies the presence of the other.