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I'm sorry for all the confusion you've had surrounding the HERneu2 status. If you get a second opinion, that onc will likely repeat the same tests and may or may not get inconclusive results. My understanding is that Herceptin will either do something or nothing, but it isn't likely to harm you, though there are a small--and I mean miniscule--number of people who can have cardiac issues as a result, but again, it's very rare, and they will do MUGA scans every 3 months to make sure there are no cardiac issues. Herceptin is not actually chemo in the real sense of the word. It's an antibody that tells the cells to stop copying themselves in women who are HERneu2+. It doesn't kills cells like chemo. It just lays the groundwork for them not reproducing. I had Herceptin every 3 weeks for a year, and truthfully it was a snap. I don't remember whether I did radiation interfered with Herceptin. I do understand your frustration with this, but I will say Herceptin really was a walk in the park. There were virtually no symptoms, except once in a awhile a runny nose. Hope that helps.
Hugs & prayers,