https://www.nature.com/articles/s41380-021-01285-w
This study focused on doses on antidepressants to effect serotonin and therefore to treat depression The sadness of those with P trait is clearly related to serotonin.
Life seems unjust to make some individuals (those with P trait) sadder than others. Why can't everyone be happy. Maybe its a matter of tradeoffs. Their sadness puts their energies into getting things done in the world?
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