Here is another example of entanglement causing lack of association in genes because both control and case studies are of punctilious predominance. Migraine seems likely associated with N/NP types so that's a problem.
It is also interesting that migraine may be an adaptive response of the N/NP individual whose CNS is too quiet. The pain of migraine is a way to keep the system alert (to increase adrenergic transmission. As such migraine would add to the list of conditions that seem to merit more NPA study, conditions including sleep apnea, narcolepsy, sudden infant death syndrome, sudden adult death, neonatal respiratory distress and asthma and COPD. It looks like that non Aggressive individuals are at most risk from their own physiology whereas Aggressive types are more at risk from tangling with the environment, including other organisms.
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