So, the prevalence of Down's syndrome in non-sanguine habitancies should be low. This seems to be the case: see graph below showing much lower mortality from Down's syndrome in Eastern Europe and Russia. (Presumably the Russian statistics are skewed toward Western Russia).
This graph is from healthgrove.com.
Looking at Brazil, which is more Corybantic (sanguine aggressive) than Bolivia, Peru or Ecuador, the rate is lower there as well:
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