Posted by Donna Hobgood on March 24, 2012, 12:42 pm, in reply to "more evidence that Fragile X syndrome doesn't see to involve narcissism or aggression traits"
http://www.ncbi.nlm.nih.gov/pubmed/15343070
And here we see that the state of dopamine in the prefrontal cortex in Fragile X syndrome appears to be too high such that dopamine neurons (like DRD2, a narcissism candidate gene) and probably other dopamine neurons have too low a neuroactivity. This would tend to mean that individuals with Narcissism trait would have no deficit of Narcissism trait. This would not in itself cause Fragile X cognitive deficits but would be coincident of the low cognitive activity in the prefrontal cortex that would correlate with a mental retardation phenotype.
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