I enjoy these a great deal, and they quite often have noir shadowing. The stories are stories of jeopardy. IMHO, these cartoons are very early in using noir graphics. Some earlier Disney cartoons might turn up similar effects. Certainly the 1940 Fantasia may have a segment that qualifies, the Sorcerer's Apprentice. Parts of that may have inspired Fleischer's Mechanical Monsters, which in any event may have inspired some of The Empire Strikes Back.
Dan Hodges may wish to take note. Some of the episodes are directly in the spy mode. Others have other sorts of enemies that stand in for the enemies faced by the country at that time.
The many superhero neo-noirs from 1980 onwards are often heavy, long-winded affairs that simply cannot and do not capture the agility of a comic book. These cartoons are able to do it, and they succeed at it.
When we see Superman in the opening shot, arms on hips, most of his face is in darkness and so is his torso. He's "lit" from the side and where there is no light, the background is a dark shade of blue. The first shot of the city and Daily Planet It is as if from an aerial view, and it's at night. The music is foreboding. The chief sits at a desk lit by one overhead bulb shaded, casting a sharp shadow effect.
The anime neo-noirs of late are much better at capturing the spirit of the superhero noir than those big movies.