Posted by TENA/MERMIE on 5/23/2007, 4:52 am Our objectives were to investigate thyroid abnormalities and autoimmunity in 120
Association between thyroid autoimmunity and Fibromyalgic disease severity
patients affected by Fibromyalgia (FM) and to study their relationships with
clinical data and symptoms.
Thyroid assessment by means of antithyroglobulin antibodies, antithyroid
peroxidase antibodies, free triiodo-thyronine, free thyroxine, and thyroid
stimulating hormone analyses was carried out. The clinical parameters
"Fibromyalgia Impact Questionnaire", pain, tender points, fatigue, and other
symptoms, and the presence of depression or anxiety disorders were evaluated.
The basal thyroid hormone levels of FM patients were in the normal range, while
41% of the patients had at least one thyroid antibody. Patients with thyroid
autoimmunity showed a higher percentage of dry eyes, burning, or pain with
urination, allodynia, blurred vision, and sore throat.
Correlations found between thyroid autoimmunity and age or with the presence of
depression or anxiety disorders were not significant. However, in the cohort of
post-menopausal patients, the frequency of thyroid autoimmunity was higher with
respect to pre-menopausal patients.
In conclusion, autoimmune thyroiditis is present in an elevated percentage of FM
patients, and it has been associated with the presence of typical symptoms of
the disease. source PRO HEALTH- research wellnesstraingroup!M!
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