Posted by Chris M. on 7/22/2008, 9:02 pm
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They are the proving grounds of Medicine and equipment and proceedures. They are trials paid for by private research, government research, foreign researchers, Us researchers. Good science requires approval of any trial, and the results, if worth anything must be then published in Medical Journals which have standing in the world as authorities on various parts or proceedures for humans. In short, the world is looking over the shoulder of researchers, and may howl if anything is fowl or poorly done. That said, it's trials of experiments to see what works and what doesn't. Why do they require some people to be in good condition without flaws of anouther sort? Trials cost money, and folks want to know first if it works on those who "relatively" healthy. Once a proceedure or drug is available to Physicians, the trials are a foundation for it's use. Why aren't they all over the country right away? Cost usually, plus not every Physician is interested in such and such treatment. Why do they have controls? If every person who takes a spoonful of their apple juice gets a new blossom on the nose, and all those who got a fake spoonful didn't- it tells you something is good for making blossoms on the noses of anyone with the basic condition. Crossovers, simply means, they switch places later to double prove. Why am I excluded? Do you have an "extra" problem they are now aware of? If someone is researching a treatment for the basic disease, they don't want to add your "extra problem" as it may confuse the issue. Happily, by excluding you at the beginning, if the product works it may come on the market sooner! Bless all those who have helped with trials.

Link: Glossary for Clinical trials